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    pard3aa par-3 family cell polarity regulator alpha, a [ Danio rerio (zebrafish) ]

    Gene ID: 101882925, updated on 25-Apr-2024

    Summary

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    Official Symbol
    pard3aaprovided by ZNC
    Official Full Name
    par-3 family cell polarity regulator alpha, aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-170531-1
    See related
    AllianceGenome:ZFIN:ZDB-GENE-170531-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    pard3b; pard3l; si:ch73-378g22.1
    Summary
    Predicted to act upstream of or within cell division. Orthologous to human PARD3 (par-3 family cell polarity regulator). [provided by Alliance of Genome Resources, Apr 2022]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    all
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    Genomic context

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    Location:
    chromosome: 24
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (1624922..2274582, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (1841544..2278508, complement)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110438344 Neighboring gene uncharacterized LOC103908653 Neighboring gene cullin 2 Neighboring gene zinc finger protein 271

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. PARD3 gene variation as candidate cause of nonsyndromic cleft palate only. Cui R, et al. J Cell Mol Med, 2022 Aug. PMID 35789100, Free PMC Article
    2. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within embryonic neurocranium morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endomembrane system IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    partitioning defective 3 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      1624922..2274582 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017353937.2 → XP_017209426.2  partitioning defective 3 homolog

      UniProtKB/TrEMBL
      A0A8M6YY70
      Conserved Domains (2) summary
      cd00992
      Location:449 → 533
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:1 → 147
      DUF3534; Domain of unknown function (DUF3534)
    Nucleotide Protein Strain
    Heading Accession and Version

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